Biomarkers of Therapeutic Response in Multiple Sclerosis: Current Status
نویسندگان
چکیده
منابع مشابه
Therapeutic Applications of Monoclonal Antibodies in Multiple Sclerosis
Despite the various therapies available, the use of monoclonal antibodies is a highly specific approach that has only recently been of interest to researchers. The properties of antibodies have led to their use in the treatment of various diseases, including cancer, Alzheimer's disease, diabetes and multiple sclerosis (MS). MS, a chronic inflammatory disease, occurs commonly in young adults. Th...
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The complexity of multiple sclerosis (MS) and the incompetence of a large number of promise treatments in MS urge us to plan new and more effective therapeutic approaches that aim to suppress ongoing autoimmune responses and induction of local endogenous regeneration. Emerging data propose that hematopoietic, mesenchymal and neural stem cells have the potential to restore self-tolerance, to pro...
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Roland Martina, Bibiana Bielekovab, Reinhard Hohlfeldc and Ursula Utzd,∗ Catalan Institute for Research and Advanced Studies and Unidad de Neuroimmunologia Clinica, Hospital Universitari Vall d’Hebron, Barcelona, Spain Department of Neurology, Waddel Center for MS, University of Cincinnati & The Neuroscience Institute, Cincinnati, OH, USA Department of Neuroimmunology, Max-Planck-Institute of N...
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Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, and CD4(+) T cells form the core immunopathogenic cascade leading to chronic inflammation. Traditionally, Th1 cells (interferon-γ-producing CD4(+) T cells) driven by interleukin 12 (IL12) were considered to be the encephalitogenic T cells in MS and experimental autoimmune encephalomyelitis (EAE), an animal model of ...
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ژورنال
عنوان ژورنال: Molecular Diagnosis & Therapy
سال: 2014
ISSN: 1177-1062,1179-2000
DOI: 10.1007/s40291-014-0117-0